Author(s):
1. Josipa Karij Trivunović, Univerzitet u Banjoj Luci, Medicinski fakultet, studijski program Dentalna medicina, Republic of Srpska, Bosnia and Herzegovina
2. Vladan Mirjanić, Medicinski fakultet Banja Luka , Republic of Srpska, Bosnia and Herzegovina

Abstract:
Stem cells are unspecialized cells that can undergo unlimited self-renewal and differentiate into more mature cells with specialized functions. They have the following characteristics: pluripotency, high migratory potential, and the ability of immune tolerance. The stem cell undergoes asymmetric division, resulting in its duplicate and a copy with differentiation potential. The duplicate plays a role in renewing the original stem cell, while the other copy further divides to create progenitor cells that enter the process of division and differentiation, leading to the formation of precursor cells directed towards development in a precisely determined direction. Through further differentiation, terminal differentiated cells are formed, capable of building new tissues or replacing previously damaged ones. After terminal differentiation, the newly formed cells assume the function of the previously damaged or destroyed ones, thus aiding in tissue defect repair. They are more accessible compared to other stem cells in the body. Until today, many orofacial stem cells have been isolated, such as DPSCs, SHED, PDLSCs, DFPCs, SCAPs, OMSCs, and ASCs. Numerous scientific studies have confirmed that dental cells are indeed stem cells.

Key words:
stem cells,pluripotency,migratory potential,immune tolerance,cell division

Thematic field:
SYMPOSIUM B - Biomaterials and nanomedicine

Date of abstract submission:
12.06.2024.

Conference:
Contemporary Materials 2024 - Savremeni Materijali

Applied paper from author