Author(s):
1. Nebojša Vasiljević, Faculty of Technology - University of East Sarajevo, Republic of Srpska, Bosnia and Herzegovina
2. Vladan Mićić, Republic of Srpska, Bosnia and Herzegovina
3. Ljubica Vasiljević, Faculty of Technology - University of East Sarajevo, Republic of Srpska, Bosnia and Herzegovina
4. Duško Kostić, University of East Sarajevo, Faculty of Technology, Republic of Srpska, Bosnia and Herzegovina
5. Jelena Perić, Republic of Srpska, Bosnia and Herzegovina
6. Mirko Radic, Faculty of Technology - University of East Sarajevo, Republic of Srpska, Bosnia and Herzegovina

Abstract:
Given that many synthetic medications can induce a variety of negative reactions in patients, a search for natural substances with minimal side effects in patients has been conducted. Nowadays, researchers are focusing on plant medicines, which have been used to heal illnesses since ancient times. The plant Crataegus monogyna Jack. (hawthorn) is the most abuntant plant in the Rosaceae family that is also used in traditional medicine. C. monogyna's pharmaceutical, phytochemical, functional, and therapeutic qualities are based on a wide range of useful secondary metabolites, which include phenolic compound (flavonoids, anthocyanins, tannins), vitamin C and antioxidants. Total (poly)phenols, flavonoids and anthocyanins contents in C. monogyna Jacq. extracts were measured using the Folin-Ciocalteu reagent, aluminium chloride and pH differential methods, respectively. The extraction lasted 15 to 120 min, with a solid-to-solvent ratio of 1:15 w/v and 1:30 w/v by using solvent of 30% ethanol. According to the results, the extraction process has the highest velocity within the first 15 min, when the majority of (poly)phenols and flavonoids are extracted, but it becomes slower as time passes. Higher yields are obtained by utilizing a solid-to-solvent ratio of 1:30 w/v rather than a solid-to-solvent ratio of 1:15 w/v, which indicates that when the amount of drug increases over a certain optimal value, the resistance to mass transfer from a solid material to liquid increases.

Key words:
anthocyanins,extraction,flavonoids,(poly)phenols,antocijani,ekstrakcija,(poli)fenoli,flavonoidi

Thematic field:
SYMPOSIUM A - Science of matter, condensed matter and physics of solid states

Date of abstract submission:
20.08.2023.

Conference:
Contemporary Materials 2023 - Savremeni materijali

Applied paper from author