Author(s):
1. Jelena Malinovic Pancic, Univerzitetski klinicki centar Banja Luka, Republic of Srpska, Bosnia and Herzegovina
2. Bojana Carić, Republic of Srpska, Bosnia and Herzegovina
3. Blaženko Vuković, Republic of Srpska, Bosnia and Herzegovina

Abstract:
The sensitivity to the action of insulin varies widely among patients, even those with normal glucose metabolism. Insulin resistance is generally defined as a subnormal biological response to normal levels of insulin and clinically refers to a situation in which administered insulin levels are associated with subnormal glycemic response. The aim of our study was to determine the effect of the application of insulin pump therapy in patients with type 1 diabetes who were previously treated with intensive insulin therapy, to the level of insulin resistance. Our study included 40 patients to whom insulin sensitivity was determined before and 6 months after the insulin pump with the method of insulin hypoglycemic clamp, The results indicate that this method of therapy in patients with type 1 diabetes compared to the intensive insulin therapy leads to a reduction in insulin resistance, the reduction in the total daily insulin dose, improvement of glycemic control parameters as well as reducing the number of episodes of hypoglycemia on a weekly basis.

Thematic field:
SYMPOSIUM B - Biomaterials and nanomedicine

Date of abstract submission:
15.07.2016.

Conference:
Contemporary Materials 2016 - Savremeni Materijali

Applied paper from author